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Dosing Quick Reference

Printable dosing charts for peptide and GLP-1 therapy. Includes titration schedules, reconstitution notes, side effect profiles, and monitoring parameters. Filter by category or print individual charts for your injection stations.

💉

Semaglutide

GLP-1 Agonist SQ Injection Weekly
Starting Dose
0.25 mg/week
Max Dose
2.4 mg/week
Titration Interval
Every 4 weeks
Maintenance
1.0–2.4 mg/wk
Titration Schedule
PhaseWeeksDoseFrequencyNotes
Initiation1–40.25 mgOnce weeklyTolerance building — not therapeutic dose
Escalation 15–80.5 mgOnce weeklyFirst therapeutic dose; assess GI tolerance
Escalation 29–121.0 mgOnce weeklyContinue if tolerated; good response may plateau here
Escalation 313–161.7 mgOnce weeklyStep up only if weight loss <5% at 1.0 mg
Maintenance17+2.4 mgOnce weeklyMax approved dose; hold at lowest effective dose

⚠️ Common Side Effects

  • Nausea, vomiting (most common during titration)
  • Diarrhea or constipation
  • Injection site reactions
  • Fatigue, headache
  • Decreased appetite

🔬 Monitoring

  • Body weight at each visit
  • A1C if diabetic (q3 months)
  • Thyroid function (baseline + annual)
  • Heart rate (may increase 1–4 bpm)
  • Renal function if borderline CKD

🚫 Contraindications

  • Personal/family Hx medullary thyroid cancer
  • MEN type 2
  • Pregnancy / breastfeeding
  • Pancreatitis history (caution)
  • Severe GI disease
🧪
Reconstitution: Typically supplied as lyophilized powder. Add 2 mL bacteriostatic water to 5 mg vial → 2,500 mcg/mL (2.5 mg/mL). For 0.25 mg dose: draw 10 units on U-100 syringe. Store reconstituted vial 28 days at 2–8°C or room temp (avoid heat/light).
💊

Tirzepatide

GIP + GLP-1 Agonist SQ Injection Weekly
Starting Dose
2.5 mg/week
Max Dose
15 mg/week
Titration Interval
Every 4 weeks
Maintenance
5–15 mg/wk
Titration Schedule
PhaseWeeksDoseFrequencyNotes
Initiation1–42.5 mgOnce weeklyTolerance dose — not therapeutic
Escalation 15–85.0 mgOnce weeklyFirst therapeutic dose; many patients respond well here
Escalation 29–127.5 mgOnce weeklyEscalate only if weight loss plateau or insufficient
Escalation 313–1610 mgOnce weeklyContinue to titrate based on patient response
Escalation 417–2012.5 mgOnce weeklyNear-max dose; use only if clinically indicated
Maximum21+15 mgOnce weeklyMax approved dose; hold at lowest effective dose

⚠️ Common Side Effects

  • Nausea (less than semaglutide at equiv. weight loss)
  • Diarrhea, constipation, vomiting
  • Decreased appetite
  • Injection site erythema
  • Hair loss (temporary, nutritional)

🔬 Monitoring

  • Body weight monthly
  • A1C, fasting glucose (q3 months if T2DM)
  • Lipase if abdominal pain develops
  • Nutrient status (zinc, iron, B12) at 6 months
  • Blood pressure, heart rate

🚫 Contraindications

  • Personal/family Hx medullary thyroid cancer
  • MEN type 2
  • Pregnancy
  • Severe renal/hepatic impairment (caution)
  • Diabetic gastroparesis
🧪
Reconstitution (18 mg vial): Add 2 mL bacteriostatic water → 9,000 mcg/mL. For 2.5 mg dose: draw 28 units (U-100). 36 mg vial: Add 2 mL BaW → 18,000 mcg/mL. 72 mg vial: Add 2 mL → 36,000 mcg/mL. Refrigerate reconstituted vial (2–8°C), stable 28 days. Bring to room temp 15 min before injection.
🧬

BPC-157

Body Protective Compound SQ / IM Daily
Standard Dose
200–500 mcg
Frequency
Once or twice daily
Cycle Length
4–12 weeks
Route
SQ or IM near injury
Dosing Protocols
ProtocolDoseFrequencyDurationIndication
Standard healing250 mcgBID (morning + evening)4–8 weeksGeneral tissue healing, GI support
Acute injury500 mcgOnce daily near site2–6 weeksTendon, ligament, muscle injury
GI protocol250–500 mcgOnce daily, oral or SQ4–8 weeksLeaky gut, IBD, GERD support
Maintenance200 mcgOnce dailyOngoing (cycle off q12 wks)Longevity, preventive

⚠️ Side Effects (Rare)

  • Nausea (usually transient)
  • Injection site redness/swelling
  • Dizziness (rare, transient)
  • Generally very well tolerated

🎯 Clinical Applications

  • Tendon/ligament/muscle repair
  • GI tract healing (ulcers, IBD)
  • Neurological recovery support
  • Post-surgical healing
  • Anti-inflammatory support

📝 Administration Notes

  • Inject near injury site when targeting musculoskeletal
  • Subcutaneous preferred for systemic effect
  • Morning administration common
  • Can combine with TB-500 for synergistic healing
🧪
Reconstitution (5 mg vial): Add 2 mL bacteriostatic water → 2,500 mcg/mL. For 250 mcg dose: draw 10 units (U-100 syringe). Refrigerate, stable 60+ days. Protect from light.
🔬

CJC-1295 / Ipamorelin

GHRH + Ghrelin Mimetic SQ Injection GH Secretagogue Stack
CJC-1295 Dose
100–300 mcg
Ipamorelin Dose
100–300 mcg
Frequency
1–3× daily
Best Timing
Before sleep / fasted
Dosing Protocols
ProtocolCJC-1295IpamorelinTimingGoal
Conservative start100 mcg100 mcgOnce daily at bedtimeAnti-aging, sleep quality
Standard protocol200 mcg200 mcgBedtime (fasted 2h)Body composition, recovery
Aggressive stack300 mcg300 mcgBID: AM + bedtimeMuscle building, fat loss
Performance200 mcg200 mcgTID: AM, post-workout, bedtimeAthletic performance, recovery

⚠️ Side Effects

  • Water retention (early, transient)
  • Flushing, head rush at injection
  • Fatigue / grogginess (especially bedtime dose)
  • Tingling extremities (carpal tunnel-like)
  • Hunger increase (Ipamorelin)

🔬 Monitoring

  • IGF-1 levels (baseline + 3 months)
  • Fasting glucose (GH can affect insulin sensitivity)
  • Body composition metrics
  • Sleep quality assessment

📝 Key Notes

  • Must inject in fasted state for optimal GH pulse
  • CJC-1295 no-DAC preferred for physiologic pulsatility
  • Combine in same syringe for convenience
  • 5-on/2-off weekly cycling recommended
🧪
Reconstitution (2 mg vials each): Add 2 mL BaW to each → 1,000 mcg/mL. For 200 mcg of each: draw 20 units from each vial into same syringe. Refrigerate, stable 30 days. Both peptides are stable when combined.
🌙

Sermorelin

GHRH Analogue SQ Injection GH Secretagogue
Standard Dose
200–500 mcg
Frequency
Once daily at bedtime
Cycle
3–6 months on
Route
SQ (abdomen or thigh)
Dosing Protocol
ProtocolDoseTimingDurationNotes
Starter dose200 mcgBedtime, fasted 2hWeeks 1–4Assess tolerance; minimal side effects expected
Standard adult300 mcgBedtime, fasted 2hMonths 2–6Most commonly used dose
Higher dose500 mcgBedtime, fasted 2hAs indicatedConsult IGF-1 labs before escalating

⚠️ Side Effects

  • Flushing at injection site
  • Headache (early, transient)
  • Fatigue, somnolence
  • Nausea (rare)
  • Antibody formation (rare, long-term)

🔬 Monitoring

  • IGF-1 levels at 3 and 6 months
  • Body composition (6-month assessment)
  • Fasting glucose
  • Bone density if indicated

🎯 Clinical Applications

  • Adult GH deficiency (diagnosed)
  • Anti-aging / longevity protocols
  • Body composition optimization
  • Sleep quality improvement
  • Recovery enhancement
🧪
Reconstitution (3 mg vial): Add 1 mL bacteriostatic water → 3,000 mcg/mL. For 300 mcg dose: draw 10 units (U-100). Refrigerate, stable 30 days at 2–8°C.
❤️

PT-141 (Bremelanotide)

Melanocortin Agonist SQ Injection / Intranasal PRN
Starting Dose
0.5–1.0 mg
Standard Dose
1.75 mg
Frequency
PRN (not daily)
Timing
30–60 min before activity
Dosing Protocol
DoseRouteTimingIndicationNotes
Test dose0.5 mg SQ45–90 min beforeFirst use / sensitivity checkAssess nausea, BP, flushing response
Low dose1.0 mg SQ45–60 min beforeMild hypoactive sexual desireGood starting point for most patients
Standard dose1.75 mg SQ45 min beforeHSDD, erectile dysfunctionFDA-approved dose for HSDD in women
Max single dose2.0 mg SQ30–60 min beforeInadequate response to 1.75 mgIncreased nausea risk; don't exceed

⚠️ Side Effects

  • Nausea (most common, dose-dependent)
  • Flushing, hot flash
  • Transient BP elevation
  • Headache
  • Spontaneous erections (men)
  • Hyperpigmentation (chronic use)

🔬 Monitoring

  • BP before first use (avoid if CV disease)
  • Assess efficacy and tolerability
  • Monitor for nausea patterns
  • Skin changes with prolonged use

🚫 Contraindications

  • Uncontrolled hypertension
  • Cardiovascular disease
  • Pregnancy
  • Use with antihypertensive medications (caution)
  • More than 1 dose per 24 hours
🧪
Reconstitution (10 mg vial): Add 2 mL bacteriostatic water → 5,000 mcg/mL. For 1.75 mg dose: draw 35 units (U-100). Refrigerate, stable 30 days at 2–8°C.
🔋

TB-500 (Thymosin Beta-4)

Tissue Repair Peptide SQ / IM Weekly
Loading Dose
2–5 mg/week
Maintenance
2 mg/bi-weekly
Loading Phase
6–8 weeks
Route
SQ or IM
Dosing Protocol
PhaseDoseFrequencyDurationPurpose
Loading (mild injury)2.0 mgTwice weekly6 weeksEstablish tissue levels for healing
Loading (significant injury)5.0 mgTwice weekly6–8 weeksAcute recovery, serious tissue damage
Maintenance2.0 mgEvery 2 weeksOngoing as neededSustain healing benefits, prevent recurrence
Performance / preventive2.5 mgOnce weekly8 weeks + breakAthletic recovery, injury prevention

⚠️ Side Effects (Generally Mild)

  • Fatigue (particularly loading phase)
  • Head rush / lightheadedness
  • Nausea (rare)
  • Injection site irritation
  • Very well tolerated overall

🎯 Clinical Applications

  • Tendon and ligament repair
  • Muscle tears and strains
  • Cardiac tissue support (post-injury)
  • Anti-inflammatory (systemic)
  • Hair growth support (emerging)

📝 Combination Notes

  • Synergistic with BPC-157 for healing
  • Can combine in same syringe as BPC-157
  • Works proximally (systemic) vs. BPC-157 local
  • Cycle 8 weeks on, 4 weeks off recommended
🧪
Reconstitution (2 mg vial): Add 1 mL bacteriostatic water → 2,000 mcg/mL. For 2 mg dose: full vial in one injection. Refrigerate, stable 30 days.
✨

GHK-Cu (Copper Peptide)

Regenerative Peptide SQ / Topical Daily
Injection Dose
1–2 mg/day
Topical
0.01–2% solution
Cycle
4–8 weeks
Routes
SQ, topical, intranasal
Dosing Protocol
RouteDoseFrequencyDurationIndication
Subcutaneous injection1–2 mgOnce daily4–8 weeksSystemic anti-aging, tissue repair, hair growth
Topical (skin)0.1–2% creamBID applicationOngoingSkin rejuvenation, collagen production, wound healing
Scalp topical0.5–1% solutionOnce daily3–6 monthsHair follicle stimulation, anti-hair loss
Intranasal100–200 mcgOnce daily4–8 weeksCognitive function, neuroprotection (emerging)

⚠️ Side Effects (Very Mild)

  • Mild skin tingling/warmth (topical)
  • Temporary skin darkening (injection site)
  • Increased copper taste (high doses)
  • Considered very safe at standard doses

🎯 Clinical Applications

  • Skin aging / collagen synthesis
  • Hair follicle regeneration
  • Wound and scar healing
  • Anti-inflammatory support
  • Antioxidant / neuroprotection

📝 Key Notes

  • Dose dependent — start low
  • Pairs well with BPC-157 for healing
  • Topical + systemic combination is synergistic
  • No receptor downregulation reported
🧪
Reconstitution (50 mg vial): Add 5 mL bacteriostatic water → 10,000 mcg/mL (10 mg/mL). For 2 mg dose: draw 20 units (U-100). Refrigerate, stable 30 days at 2–8°C. Can prepare topical solution by diluting further in sterile saline.
⚕️

For Licensed Healthcare Providers Only. These dosing charts are for educational reference and are intended for use by licensed physicians, nurse practitioners, and credentialed clinical staff.

All dosing information should be verified against current prescribing references and peer-reviewed literature before clinical application. Compounded medications are not FDA-approved drug products. Individual patient factors — including weight, kidney function, comorbidities, and medication interactions — must be considered. The prescriber assumes full responsibility for clinical decisions.